A Clinical study on the management of Mutrakrichchra with Trikantakadya Guggulu

Abstract

The disease ‘Mutrakrichchra’ has cardinal feature of burning micturition. Thus, needs recognition to explore the newer therapeutic possibilities. It resembles Urinary Tract Infections in modern parlance which is major health problems affecting millions of each year and frequent visits are seen in OPD in day to day practice. The present study is undertaken to evaluate the efficacy of Trikantakadaya Guggulu in    the management of Mutrakrichchra. to Urinary Tract Infections. Objective: To evaluate the therapeutic effect of Trikantakadya Guggulu individually in patients suffering from Mutakrichchra. Study Design: Prospective open labelled clinical study conducted in daily clinical practice Methods. Subjects were advised to take “Trikantakadya Guggulu” 1500 mg TDS for 14 days with Anupana Luke warm water. 30 subjects completed the study. The primary endpoints were changes in urine routine microscopic in pus cells. The secondary outcomes were dysuria, pain reduced. Results- At baseline visit the mean value of pus cell 14.7 ± 6.54 which reduced highly significant 4.93 ± 4.55 on day 14. The mean value of Epithelial cells at baseline 4.967±6.505 which reduced significantly 2.800 ± 3.347 on day 14. The mean score of RBCs at baseline 0.667 ± 0.758 which reduced significantly 0.433 ± 0.568. Vitals and all the safety laboratory parameters were within normal limit both at baseline and day 14^th. Conclusion Trikantakadya Guggulu is safe and significantly effective in reducing, pus cells dysuria, pain and  burning micturition CTRI registration No is CTRI/2019/02/017741.